Asthma Causes And Treatment
Asthma is an inflammatory disorder of the airways,
characterized by periodic attacks of wheezing,
shortness of breath, chest tightness, and coughing.
The inflammation of the airways causes airflow
into and out of the lungs to be restricted. These
symptoms can be triggered by Exposure to tobacco
or wood smoke, Breathing polluted air, Inhaling
other respiratory irritants such as perfumes
or cleaning products, Exposure to airway irritants
at the workplace, Breathing in allergy-causing
substances (inhaled allergens) such as molds,
dust,
dust mites, pollen or animal dander, Emotional
excitement or stress, Food or drug allergies,
Respiratory infections such as a cold, flu, sinusitis,
or bronchitis,
Exposure to cold, dry weather and Physical exertion
or exercise.
With proper self management and medical treatment,
symptoms can be decreased and most patients can lead
normal lives although there is no cure for asthma.
Treatment involves the use of rescue and control
medications. Rescue medications are taken after an
asthma attack has already begun. Short-acting beta-agonists
are the most commonly used rescue medications. Inhaled
short-acting beta-agonists work rapidly, within minutes,
to open the breathing passages, and the effects usually
last 4 hours.
Albuterol is the most frequently used short-acting
beta-agonist medication. Anticholinergics are another
class of drugs useful as rescue medications during
asthma attacks. Inhaled anticholinergic drugs open
the breathing passages, similar to the action of
the beta-agonists. Ipratropium bromide is the inhaled
anticholinergic drug currently used as a rescue medicine.
Controller medicines help minimize the inflammation
that causes an acute asthma attack. Long-acting beta-agonists
are drugs chemically related to adrenaline, a hormone
produced by the adrenal glands. Inhaled long-acting
beta-agonists work to keep breathing passages open
for 12 hours or longer. They relax the muscles of
the breathing passages, dilating the passages and
decreasing the resistance to exhaled airflow, making
it easier to breathe. Salmeterol and formoterol are
long-acting beta-agonists.
Inhaled corticosteroids are the main class of medications
in this group that act locally by concentrating their
effects directly within the breathing passages. Beclomethasone
and triamcinolone are examples of inhaled corticosteroids.
Leukotriene inhibitors are another group of drugs
that work by blocking the chemicals that produce
inflammatory response and thus reduce inflammation.
Zileuton, zafirlukast and montelukast are examples
of leukotriene inhibitors. Cromolyn sodium is another
medication that can prevent the release of chemicals
that cause asthma-related inflammation and is especially
useful for people who develop asthma attacks in response
to certain types of allergic exposures. Following
preventive measures is another important step that
will in reducing attacks and the use of medication.
All known allergens and respiratory irritants should
be eliminated from the house. Exposure to dust mites
and moulds can be reduced by encasing mattresses
and pillows in allergy-impermeable covers, removing
carpets and by vacuuming the house regularly as well
as lowering indoor humidity. Allergy desensitization
may also be helpful in reducing asthma symptoms and
medication use.